Sel tunjang hematopoiesis

*Sel dasar hematopoietik*
Sel dasar hematopoietik
	Gambaran keseluruhan haematopoiesis manusia biasa
Butiran
Pendahulu	Hemangioblas
Sistem	Sistem hematopoietik
Lokasi	Sumsum tulang
Fungsi	Sel dasar yang menimbulkan sel darah yang lain
Pengenalpastian
nama bahasa Latin	Cellula haematopoietica praecursoria
Akronim	HSC
MeSH	D006412
TH	H2.00.01.0.00006
	Istilah anatomi mikroanatomi; [sunting di Wikidata]

Sel dasar hematopoietik (HSC, bahasa Inggeris: hematopoietic stem cellcode: en is deprecated ) ialah sel dasar ^[1]yang menimbulkan sel darah yang lain. Proses tersebut dipanggil hematopoiesis.^[2] Dalam vertebrat, HSC muktamad yang pertama timbul daripada dinding endotelium ventral aorta embrio di dalam kawasan aorta-gonad-mesonefros (gestasi tengah), melalui proses yang dikenali sebagai peralihan endotelium-ke-hematopoietik.^[3]^[4] Di dalam orang dewasa, hematopoiesis berlaku di sumsum tulang merah, di teras kebanyakan tulang. Sumsum tulang merah terbit daripada lapisan embrio yang dipanggil mesoderma.

Lihat juga

Nic sel dasar hematopoietik

Rujukan

^ Monga I, Kaur K, Dhanda S (March 2022). "Revisiting hematopoiesis: applications of the bulk and single-cell transcriptomics dissecting transcriptional heterogeneity in hematopoietic stem cells". Briefings in Functional Genomics. 21 (3): 159–176. doi:10.1093/bfgp/elac002. PMID 35265979 Check |pmid= value (bantuan).
^ Birbrair A, Frenette PS (April 2016). "Niche heterogeneity in the bone marrow". Annals of the New York Academy of Sciences. 1370 (1): 82–96. Bibcode:2016NYASA1370...82B. doi:10.1111/nyas.13016. PMC 4938003. PMID 27015419.
^ Dzierzak E, Bigas A (May 2018). "Blood Development: Hematopoietic Stem Cell Dependence and Independence". Cell Stem Cell. 22 (5): 639–651. doi:10.1016/j.stem.2018.04.015. hdl:10230/36965. PMID 29727679.
^ Ottersbach K (April 2019). "Endothelial-to-haematopoietic transition: an update on the process of making blood". Biochemical Society Transactions. 47 (2): 591–601. doi:10.1042/BST20180320. PMC 6490701. PMID 30902922.

Pautan luar

Fact sheet about blood stem cells on EuroStemCell

[Monga-1] Monga I, Kaur K, Dhanda S (March 2022). "Revisiting hematopoiesis: applications of the bulk and single-cell transcriptomics dissecting transcriptional heterogeneity in hematopoietic stem cells". Briefings in Functional Genomics. 21 (3): 159–176. doi:10.1093/bfgp/elac002. PMID 35265979 Check |pmid= value (bantuan).

[Birbrair_n/a–n/a-2] Birbrair A, Frenette PS (April 2016). "Niche heterogeneity in the bone marrow". Annals of the New York Academy of Sciences. 1370 (1): 82–96. Bibcode:2016NYASA1370...82B. doi:10.1111/nyas.13016. PMC 4938003. PMID 27015419.

[:0-3] Dzierzak E, Bigas A (May 2018). "Blood Development: Hematopoietic Stem Cell Dependence and Independence". Cell Stem Cell. 22 (5): 639–651. doi:10.1016/j.stem.2018.04.015. hdl:10230/36965. PMID 29727679.

[4] Ottersbach K (April 2019). "Endothelial-to-haematopoietic transition: an update on the process of making blood". Biochemical Society Transactions. 47 (2): 591–601. doi:10.1042/BST20180320. PMC 6490701. PMID 30902922.

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