Joachim Frank
Joachim Frank (lahir 12 September 1940) ialah seorang ahli biofizik Amerika kelahiran Jerman di Universiti Columbia dan seorang pemenang Hadiah Nobel. Beliau dianggap sebagai pengasas mikroskopi elektron tunggal-zarah (cryo-EM), yang mana beliau berkongsi Hadiah Nobel dalam Kimia pada tahun 2017 bersama Jacques Dubochet dan Richard Henderson.[2] Beliau juga telah memberikan sumbangan penting kepada struktur dan fungsi ribosom daripada bakteria dan eukariota.
Joachim Frank | |
|---|---|
 Joachim Frank di sidang akhbar Nobel di Stockholm, Disember 2017 | |
| Kelahiran | 12 September 1940 |
| Kerakyatan | Amerika Syarikat, Jerman[1] |
| Pendidikan | Universiti Freiburg (BS) University of Munich (MS) Max Planck Society Technical University of Munich (PhD) |
| Terkenal kerana | Mikroskopi krio-elektron tunggal-zarah Struktur dan dinamik ribosom |
| Pasangan | Carol Saginaw (k. 1983) |
| Anak-anak | Ze Frank & Mariel Frank |
| Anugerah | Benjamin Franklin Medal in Life Science (2014) Wiley Prize in Biomedical Sciences (2017) Hadiah Nobel dalam Kimia (2017) |
| Kerjaya saintifik | |
| Bidang | Biologi struktur Mikroskopi krio-elektron tunggal-zarah |
| Institusi | Columbia University College of Physicians and Surgeons, Department of Biochemistry and Molecular Biophysics |
| Tesis | Untersuchungen von elektronenmikroskopischen Aufnahmen hoher Auflösung mit Bilddifferenz- und Rekonstruktionsverfahren (1970) |
| Penasihat kedoktoran | Walter Hoppe |
| Penasihat akademik yang lain | Robert M. Glaeser, Robert Nathan |
Anugerah
sunting- 1994 Humboldt Research Award of the Alexander von Humboldt Foundation
- 2006 Fellow of the American Academy of Arts and Sciences[3]
- 2006 Member of the National Academy of Sciences[4]
- 2014 Benjamin Franklin Medal in Life Science of the Franklin Institute[5]
- 2017 Wiley Prize in Biomedical Sciences[6]
- 2017 Nobel Prize in Chemistry[7]
- 2018 Honorary Doctorate, University of Siegen (Germany)[8]
Penerbitan terpilih
suntingBuku
sunting- Frank, Joachim (2014), Found in Translation – Collection of Original Articles on Single-Particle Reconstruction and the Structural Basis of Protein Synthesis, Singapore: World Scientific Press, ISBN 978-9814522809.
- Frank, Joachim (2011), Molecular Machines in Biology: Workshop of the Cell, Cambridge: Cambridge University Press, ISBN 978-0-521-19428-0.
- Glaeser, Robert M.; Downing, Ken; Chiu, Wah; Frank, Joachim; DeRosier, David (2007), Electron Crystallography of Biological Macromolecules, Oxford: Oxford University Press, ISBN 978-0-19-508871-7.
- Frank, Joachim (2006), Electron Tomography (ed. 2nd), New York: Springer, ISBN 978-0387312347.
- Frank, Joachim (2006), Three-Dimensional Electron Microscopy of Macromolecular Assemblies (ed. 2nd), Oxford: Oxford University Press, ISBN 978-0195182187.
Rencana
sunting- Frank, Joachim (2015). "Generalized single-particle cryo-EM – a historical perspective". Microscopy. 65: 3–8. doi:10.1093/jmicro/dfv358. PMC 4749046. PMID 26566976.
- Frank, Joachim; Gonzalez, Jr., Ruben L. (2010). "Structure and dynamics of a processive Brownian motor: the translating ribosome". Annu. Rev. Biochem. 79: 381–412. doi:10.1146/annurev-biochem-060408-173330. PMC 2917226. PMID 20235828.
- Frank, Joachim; Spahn, , Christian M.T (2010). "The ribosome and the mechanism of protein synthesis". Rep. Progr. Phys. 69: 1383–1417. doi:10.1088/0034-4885/69/5/R03.
- Frank, Joachim (2009). "Single-particle reconstruction of biological macromolecules in electron microscopy -- 30 years". Q. Rev. Biophys. 42: 139–158. doi:10.1017/S0033583509990059. PMC 2844734. PMID 20025794.
Rujukan
sunting- ^ Frank, Joachim (2017), Curriculum Vitae Diarkibkan 2017-10-09 di Wayback Machine. Retrieved October 4, 2017.
- ^ "The Nobel Prize in Chemistry 2017". The Nobel Foundation. October 4, 2017. Dicapai pada October 6, 2017.
- ^ Book of Members 1780–present (PDF, 878 kB) at American Academy of Arts and Sciences (amacad.org); Retrieved February 23, 2017.
- ^ "Joachim Frank". nasonline.org. January 12, 2006. Dicapai pada February 23, 2017.
- ^ "Joachim Frank". fi.edu. December 12, 2014. Dicapai pada February 23, 2017.
- ^ "The 16th Annual Wiley Prize in Biomedical Sciences Awarded for Pioneering Developments in Electron Microscopy". newsroom.wiley.com. February 22, 2017. Diarkibkan daripada yang asal pada 2017-10-04. Dicapai pada February 23, 2017.
- ^ "Nobel Prize in Chemistry Awarded for Cryo-Electron Microscopy". The New York Times. October 4, 2017. Dicapai pada 4 October 2017.
- ^ "Respect and Recognition". uni-siegen.de. April 17, 2018. Dicapai pada October 2, 2018.
Bacaan lanjut
sunting- Mossman, Kaspar (December 11, 2007). "Profile of Joachim Frank". Proceedings of the National Academy of Sciences of the USA. 104: 19668. doi:10.1073/pnas.0710323105. PMC 2148354.
Pautan luar
sunting- Frank Lab website
- List of Publications